THE RECORD
What changed
The project completed about 92% of the reference in 2003; the T2T consortium filled major gaps in 2022.
EVIDENCE
What remains
Public sequence data, maps, papers and ELSI records preserve science and ethics.
WHY IT MATTERS
Why it matters
It transformed disease research, but one reference cannot represent all human diversity.
OPEN QUESTION
Where interpretation begins
A finished sequence is not finished precision medicine; privacy, discrimination, consent and representation persist.