SALGIL ESSAY / 28
Can Humans Rewrite Life?
Examines what CRISPR makes possible and the boundaries of responsibility around therapy, inheritance, and inequality.
A tool for editing life’s text
CRISPR-Cas9 can target and alter selected DNA sequences, expanding possibilities in disease research, therapy, and crops.
‘Rewriting the code of life’ is powerful language, but it does not mean arbitrary control over traits. Gene effects emerge through other genes, cells, and environments.
- The Nobel Prize in Chemistry 2020
The official account of CRISPR-Cas9 and its applications.
Between therapy and inheritance
Editing a patient’s somatic cells and changing an embryo in a way inherited by descendants create different ranges of responsibility. The latter reaches future people who cannot consent.
Safety alone does not settle the issue. We must also ask what counts as disease, who receives access, and whether inequality or discrimination grows.
- WHO, Human genome editing recommendations
International recommendations on governance of somatic, germline, and heritable editing.
Care before creation
Genome editing does not mean humans created life from nothing. It is an ability to intervene in existing living processes.
If divine resemblance emphasizes power, living with life emphasizes limits. Institutions must observe and answer for consequences as carefully as laboratories extend capability.
Continue through the ordered exploration sequence.